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Test Name:
Treponema pallidum IgG Antibody (FTA-ABS), Serum


  • SBMF No:
    28030
  • Performance Lab Name:
    Immunology
  • Test Mnemonic:
    FTA
  • ABN:
    Not required
  • CPT Code:
    86780
  • LOINC Code:
    17726-1
  • Also Known As:
    FTA-ABS
    Fluorescent Treponemal Antibody-Absorption, Serum
  • Also See:
    28244 Treponema pallidum IgG Antibody, by MFI, with RPR Titer if Indicated
  • Spec Type:
    Serum
  • Spec Container:
    Gold top (SST) or red top (serum) tube
  • Pref Vol:
    1.0 mL
  • Min Vol:
    0.2 mL
  • Fasting:
    No
  • Spec Collect:
    Routine venipuncture
  • Spec Process:
    Clot 30 minutes
    Promptly centrifuge 15 minutes
    Immediately transfer serum to separate plastic tube
    Properly centrifuged gel barrier tube sample does not require transfer of serum to separate tube
  • Spec Store Transport:
    Refrigerated
  • Spec Stability:
    5 days refrigerated (2-8°C)
    Greater than 5 days, freeze (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles
  • Spec Reject:
    Hemolyzed or lipemic sample
  • Methodology:
    Indirect Fluorescent Antibody (IFA)
  • Use:
    Confirmation of syphilis screening tests
  • Clinical Significance:
    Fluorescent Treponemal Antibody-absorbed (FTA-ABS) is a confirmatory test procedure for syphilis screening procedures. Although the FTA-ABS procedure is more specific, the relatively low incidence of false positive FTA-ABS reactions emphasizes the need to interpret serological results in the light of the patients complete history and clinical picture. The FTA-ABS procedure is the method most recommended for confirming positive reagin tests. When the FTA-ABS test was compared to other procedures, the FTA-ABS test was shown to provide greater sensitivity and clinical correlation, particularly in untreated cases of syphilis.
  • Reference Range:
    Non-reactive
  • Day Run:
    Wed, Sat
  • Time Run:
    8:00 am
  • Time Reported:
    5:00 pm
  • Test Type:
    INFECTIOUS ANTIBODY