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Test Name:
Chlamydia IgG and IgM Antibody Panel
- SBMF No:
28017 - Performance Lab Name:
Manual Lab - Test Mnemonic:
CHL AB G/M - ABN:
Not required - CPT Code:
86631x3; 86632x3 - LOINC Code:
6919-5; 6913-8; 6916-1; 6920-3; 6914-6; 6917-9 - Test Includes:
Chlamydia pneumoniae IgG & IgM Antibodies
Chlamydia psittaci IgG & IgM Antibodies
Chlamydia trachomatis IgG & IgM Antibodies - Also Known As:
Chlamydia IgG and IgM Antibodies
Chlamydia Serology
Lymphogranuloma Venereum (LGV) Antibodies - Spec Type:
Serum - Spec Container:
Gold top (SST) or red top (serum) tube - Pref Vol:
1.0 mL - Min Vol:
0.5 mL - Fasting:
No - Spec Collect:
Routine venipuncture
Parallel testing is preferred
Label samples as: "acute" or "convalescent"
Convalescent samples must be received within 30 days from receipt of acute samples - Spec Process:
Clot 30 minutes
Promptly centrifuge 15 minutes
Immediately transfer serum to separate plastic tube - Spec Store Transport:
Refrigerated (48 hours) or frozen - Spec Stability:
8 hours room temperature (20-30°C)
48 hours refrigerated (2-8°C)
Greater than 48 hours, freeze (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles - Spec Reject:
Hemolyzed, lipemic, heat-inactivated or contaminated specimen - Spec Remarks:
Separate serum from cells ASAP - Methodology:
Micro-Immunofluorescent Assay (MIF) - Use:
The combination of IgG and IgM antibody detection is indicated for testing pneumonia patients as an aid in diagnosing community-acquired penumonia caused by Chlamydia pneumoniae - Clinical Significance:
Chlamydia are intracellular microorganisms that have some features similar to bacteria including susceptibility to antibiotic therapy as well as other features of viruses including the requirement of living cells for multiplication. C. pneumoniae causes pneumonia in humans and is spread from human to human without intermediate hosts. C. psittaci causes a disease characterized by pneumonia, headache, and hepatosplenomegaly. It is acquired by airborne transmission from infected birds. C. trachomatis has been implicated in a variety of diseases including ophthalmic infections, non-gonococcal urethritis and cervicitis, pelvic inflammatory disease in females and epididymitis in males.Approximately 40% to 60% of adult populations around the world have antibodies to C. pneumonia, which suggests that the infection is extraordinarily prevalent, and re-infection is common. Reported cases of C psittaci infection in the U.S. runs typically less than 50 per year, with 16 cases reported in 1999. Sources of human C. psittaci infection other than infected birds have been identified and may be more common than currently recognized. The prevalence of C. trachomatis infections in adolescent women usually exceeds 10% and in some populations can reach 40%. - Reference Range:
Chlamydia pneumoniae IgG titer <1:64
Chlamydia psittaci IgG titer <1:64
Chlamydia trachomatis IgG titer <1:64
Chlamydia pneumoniae IgM titer <1:10
Chlamydia psittaci IgM titer <1:10
Chlamydia trachomatis IgM titer <1:10 - Day Run:
Sat - Time Run:
6:00 am - Time Reported:
5:00 pm if neg - Test Type:
INFECTIOUS ANTIBODY