SBMF Online Payment ▶

test directorySearch Results

Click here to search again.

Test Name:
Infectious Mononucleosis Screen


  • SBMF No:
    28015
  • Performance Lab Name:
    Automated Lab
  • Test Mnemonic:
    INF MONO
  • ABN:
    Not required
  • CPT Code:
    86308
  • LOINC Code:
    5213-4
  • Also Known As:
    Heterophile Antibody
    Screen for Infectious Mononucleosis
    Mono Test
  • Spec Type:
    Serum
  • Spec Container:
    Gold top (SST) or red top (serum) tube
  • Alt Spec Type:
    Plasma
  • Alt Spec Container:
    Lavender top (EDTA) tube
  • Pref Vol:
    1.0 mL
  • Min Vol:
    0.5 mL
  • Fasting:
    No
  • Spec Collect:
    Routine venipuncture
  • Spec Process:
    Serum sample tubes, clot 30 minutes
    Promptly centrifuge 15 minutes
    Immediately transfer serum or plasma to separate plastic tube
    Properly centrifuged gel barrier tube sample does not require transfer of serum to separate tube
  • Spec Store Transport:
    Refrigerated (48 hours) or frozen
  • Spec Stability:
    Plasma: 24 hours refrigerated (2-8°C)
    Serum: 48 hours refrigerated (2-8°C)
    Greater than 48 hours, freeze (-20°C)
  • Spec Reject:
    Severely hemolyzed sample
  • Methodology:
    Latex Agglutination
  • Use:
    Diagnose infectious mononucleosis
  • Clinical Significance:
    Heterophile antibody has been rarely associated with disease states other than infectious mononucleosis, such as leukemia, cytomegalovirus, Burkitt's lymphoma, rheumatoid arthritis, and viral hepatitis. A single heterophile antibody titer is considered to have no relation to the severity of the disease, but sequential titer determinations may be useful in following the course of an individual patient. Although most patients (90%) will have a detectable heterophile level within three weeks of infection, occasionally a patient with strong clinical signs of infectious mononucleosis may take as long as three months to develop a detectable level. The heterophile test or mononucleosis slide test is probably the best test for detecting acute Epstein-Barr virus (EBV) infection. Negative results are more common in children. If further testing is desired, collect additional specimens and retest every few days. EBV infection can also be established, especially in "monospot-negative" cases, with the use of EBV IgM-specific serologies.
  • Reference Range:
    Negative
  • Day Run:
    Sun-Sat (daily)
  • Time Run:
    As received
  • Time Reported:
    5:00 pm
  • Test Type:
    INFECTIOUS ANTIBODY

Home > Test Directory > Search Results

Test Directory