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Test Name:
Chlamydia IgM Antibody Panel
- SBMF No:
28004 - Performance Lab Name:
Manual Lab - Test Mnemonic:
CHL IGM - ABN:
Not required - CPT Code:
86632x3 - LOINC Code:
6920-3; 6913-8; 6916-1 - Test Includes:
Chlamydia trachomatis IgM Antibodies
Chlamydia pneumoniae IgM Antibodies
Chlamydia psittaci IgM Antibodies - Also Known As:
C. pneumoniae IgM Antibodies
C. psittaci IgM Antibodies
C. trachomatis IgM Antibodies - Spec Type:
Serum - Spec Container:
Gold top (SST) or red top (serum) tube - Pref Vol:
1.0 mL - Min Vol:
0.5 mL - Fasting:
No - Spec Collect:
Routine venipuncture
Parallel testing is preferred
Label samples as: "acute" or "convalescent"
Convalescent samples must be received within 30 days from receipt of acute samples - Spec Process:
Clot 30 minutes
Promptly centrifuge 15 minutes
Immediately transfer serum to separate plastic tube - Spec Store Transport:
Refrigerated (48 hours) or frozen - Spec Stability:
8 hours room temperature (20-30°C)
48 hours refrigerated (2-8°C)
Greater than 48 hours, freeze (-20°C) – Do not use frost-free units that undergo repeated freeze/thaw cycles - Spec Reject:
Hemolyzed, lipemic, heat-inactivated or contaminated specimen - Spec Remarks:
Separate serum from cells ASAP - Methodology:
Micro-Immunofluorescent Assay (MIF) - Use:
The combination of IgG and IgM antibody detection is indicated for testing pneumonia patients as an aid in diagnosing community-acquired penumonia caused by Chlamydia pneumoniae - Clinical Significance:
Chlamydia are intracellular microorganisms that have some features similar to bacteria including susceptibility to antibiotic therapy as well as other features of viruses including the requirement of living cells for multiplication. C. pneumoniae causes pneumonia in humans and is spread from human to human without intermediate hosts. C. psittaci causes a disease characterized by pneumonia, headache, and hepatosplenomegaly. It is acquired by airborne transmission from infected birds. C. trachomatis has been implicated in a variety of diseases including ophthalmic infections, non-gonococcal urethritis and cervicitis, pelvic inflammatory disease in females and epididymitis in males. - Reference Range:
Chlamydia pneumoniae IgM titer <1:10
Chlamydia psittaci IgM titer <1:10
Chlamydia trachomatis IgM titer <1:10 - Additional Test Info:
IgG levels greater than or equal to 1:64 - consistent with chlamydial infections of undetermined time
High titers (greater than or equal to 1:512) - suggestive of current infection
If initial titers <1:512, second specimen collected 10-21 days later tested in parallel with first
4-fold or > rise in titer indicates current infection
Unchanging titers between 1:64 and 1:512 - suggest past infection - Day Run:
Sat - Time Run:
6:00 am - Time Reported:
5:00 pm if neg - Test Type:
INFECTIOUS ANTIBODY
