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Test Name:
Bleeding Time, Ivy
- SBMF No:
25013 - Performance Lab Name:
Hospital Lab - Test Mnemonic:
IVY - ABN:
Not required - CPT Code:
85002 - LOINC Code:
3179-9 - Also Known As:
Ivy Bleeding Time
Template Bleeding Time - Spec Type:
Point-of-Care Test (collected and performed by laboratory personnel) - Fasting:
No - Patient Prep:
Verify that patient platelet count is be least 75,000/mm3 before proceeding with test
Before testing begins, inform patient, that as with any bleeding time procedure, the possibility of faint scarring exists (keloid formation, though rare, may occur with certain patients) - Spec Collect:
Laboratory personnel will follow a prescribed procedure for collecting and performing the test - Methodology:
Surgicutt Bleeding Device - Use:
Used as a measure of the function of platelets as well as the integrity of the vessel wall - Clinical Significance:
Bleeding time is defined as the time from the making of a small incision to the time the bleeding stops. The duration of bleeding from a standard wound of the skin is a measure of the function of platelets as well as the integrity of the vessel wall. In the Ivy method, an attempt is made to control variations caused by alterations in capillary tonus by using a blood pressure cuff at a pressure between 20 mmHg and 40 mmHg, depending on patient’s age and weight. - Reference Range:
Less than 8 minutes - Critical High Value:
Greater than 20 minutes - Additional Test Info:
Ideally, platelet counts should be done before the bleeding time is performed. If the count is less than 75,000/mm3, a bleeding time may not be indicated and may even be contraindicated. Consult a pathologist.
Since the bleeding time of many people is increased after the ingestion of aspirin, it is important to determine if the patient has consumed aspirin or aspirin-containing drugs within one week prior to test.
The patient should be informed, before testing begins, that, as with any bleeding time procedure, the possibility of faint scarring exists. Keloid formation, though rare, may occur with certain patients.
Drugs capable of inducing a prolonged bleeding time in the presence of a normal platelet count include:
Antibiotics
– Ampicillin
– Mithramycin
– Nitrofurantoin
– Ticarcillin
– Azolocillin
– Moxalactam
– Penicillin
– Carbenicillin
– Nafcillin
– Piperacillin
Anti–inflammatory
– Aspirin
– Indomethacin
– Naproxen
Anticoagulants
– Dextran
– Heparin
– Prostacyclin
Miscellaneous
– Aminocaproic Acid
– Halothane
– Radiographaic contrast agents
– Ethanol
– Nitroglycerin
– Fish oil (megadoses)
Some acquired and hereditary disorders may be associated with prolonged bleeding times, but do not always result in prolonged bleeding time:
Acquired disorders
– Acquired von Willebrand’s disease
– Hairy cell leukemia
– Leukemia
– Cardiopulmonary bypass
– Hemoperfusion
– Liver disease
– Drug–induced disorders
– Hypothyroidism
– Myelodysplastic disorders
– Hairy cell leukemia
– Szechwan purpura
– Myeloproliferative disorders
– Disseminated intravascular coagulation (DIC)
– Idiopathic thrombocytopenia purpura
Hereditary disorders
– Abnormalities of primary aggregation
~ Glanzmann’s thrombasthenia – Abnormalities of secondary aggregation
~ Afibrinogenemia
~ Oculocutaneous albinism (Hermansky–Pudlak)
~ Storage pool disease
~ Cyclo–oxygenase deficiency
~ Wiskott –Aldrich syndrome
~ Release defect
– Abnormalities of adhesion
~ Bernard–Soulier (giant platelet) syndrome
~ EhlersDanlos syndrome
~ von Willebrand’s disease
– Miscellaneous disorders
~ Dysfibrinogenemia
~ Glycogen storage disease, type I
~ Osteogenesis imperfecta
~ Factor V deficiency
~ Homozygous B–thalessemia
~ Congenital heart
~ Factor VIII deficiency - Day Run:
Sun-Sat (daily) - Time Run:
As received - Time Reported:
20 minutes - Test Type:
COAGULATION
