South Bend Medical Foundation - Your Community Laboratory

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Test Name:
Heavy Metals, Whole Blood

• SBMF No:
  23380
• Performance Lab Name:
  Manual Lab
• Test Mnemonic:
  HMSB-
• ABN:
  Not required
• CPT Code:
  82175; 82300; 83655; 83825
• LOINC Code:
  31208-2; 32624-9; 42784-9; 29298-7; 56799-0; 5685-3; 5583-0; 5671-3; 5609-3
• Test Includes:
  Arsenic (As)
  Cadmium (Cd)
  Mercury (Hg)
  Lead (Pb)
• Also Known As:
  Arsenic
  As
  Cadmium
  Cd
  Lead
  Pb
  Mercury
  Hg
• Also See:
  23383 Arsenic, Whole Blood
  23382 Cadmium, Whole Blood
  23081 Lead, Whole Blood
  23381 Mercury, Whole Blood
• Spec Type:
  Whole blood
• Spec Container:
  Dark blue (royal) top (trace metal-free - EDTA) tube
      IMPORTANT: Do not use dark blue (royal) top (trace metal-free - serum) tube
• Pref Vol:
  2.5 mL
• Min Vol:
  1.0 mL
• Fasting:
  No
• Patient Prep:
  Avoid ingestion of seafood for 48 hours before specimen collected
• Spec Collect:
  Routine venipuncture
  For collection, use whole blood dark blue (royal) top tube (K2 EDTA additive, trace metal-free)
       – IMPORTANT: Do not use dark blue (royal) top serum tube (no additive, trace metal-free)
• Spec Process:
  Do not centrifuge
  Do not remove plasma from cells
• Spec Store Transport:
  Refrigerated
• Spec Stability:
  1 week refrigerated (2-8°C)
• Methodology:
  Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)
• Use:
  Screen for heavy metal poisoning
• Clinical Significance:
  The level of trace elements in human body fluids is of great importance for the diagnosis and treatment of a patient’s condition.
  It is also crucial to monitor individuals who may be exposed to high levels of toxins, such as lead and arsenic.
• Reference Range:
  

  Arsenic, Whole Blood

  Less than 70 µg/dL
  Chronic poisoning: 100-500 µg/dL
  Acute poisoning: greater than 500 µg/dL
  NOTE: Blood arsenic levels have a short half-life and are useful only within a few days of exposure

  Cadmium, Whole Blood

  Less than 5.0 µg/dL
  Values indicating excessive exposure: greater than 10 µg/dL
  Acute toxicity: greater than 50 µg/dL

  Mercury, Whole Blood

  Less than 5 µg/dL
  Mild routine exposure during work, such as dentist: less than 15 µg/dL
  Significant toxic exposure: greater than 50 µg/dL

  Lead, Whole Blood

  Adult: less than 20 µg/dL
  Occupationally Lead-Exposed Adult: less than or equal to 40 µg/dL
  Toxic: equal to or greater than 60 µg/dL
  Children:

  CDC Classification for Children
  Class	Lead µg/dL	Comment
  I	≤ 9	Not considered "lead-poisoned"
  IIA	10–14	Rescreen frequently and consider prevention activities
  IIB	15–19	Should receive nutritional and educational interventions
  III	20–44	Should receive environmental evaluation; consider chelation therapy
  IV	45–69	Needs environmental intervention and chelation therapy
  V	≥ 70	Medical emergency; medical and environmental interventions should begin immediately

• Day Run:
  Mon, Tue, Thu, Fri
• Time Run:
  8:00 am
• Time Reported:
  5:00 pm
• Test Type:
  CHEMISTRY