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Test Name:
Sodium, Urine, 24-Hour
- SBMF No:
23342 - Performance Lab Name:
Automated Lab - Test Mnemonic:
U NA24 - ABN:
Not required - CPT Code:
84300 - LOINC Code:
2955-3; 2956-1 - Test Includes:
Sodium
Creatinine - Also Known As:
Na - Spec Type:
Urine, 24-hour - Spec Container:
Plastic container with tightly fitting lid (no preservative) - Pref Vol:
20.0 mL aliquot from well-mixed 24-hour collection
Note: Send urine aliquot with notation of entire 24-hour urine volume on aliquot label and on requisition - Min Vol:
10.0 mL aliquot from well-mixed 24-hour collection - Fasting:
No - Spec Collect:
To begin collection of timed specimen, have patient urinate, noting date and exact time
Discard this first portion of urine, but document date and time of voiding on container label and test requisition as "start" of timed specimen
Save all urine voided during designated time period, including portion voided at exact end of time period
IMPORTANT: Refrigerate entire specimen (2-8°C) during and after collection to prevent bacterial growth
Document date and time of final voiding on label and requisition as "end" of timed specimen - Spec Process:
Upon completion of the collection, mix entire specimen well and measure 24-hour volume
Pour off 20.0 mL of urine into separate plastic tube(s)
Refrigerate urine aliquot and transport refrigerated
Send urine aliquot with notation of entire 24-hour urine volume on aliquot label and on requisition - Spec Store Transport:
Refrigerated - Spec Stability:
3 days refrigerated (2-8°C) - Spec Remarks:
Note: 24-hour urine is optimal specimen for testing - Methodology:
Ion-selective Electrode (ISE) - Use:
Used in the diagnosis and treatment of aldosteronism (excessive secretion of the hormone aldosterone), diabetes insipidus (chronic excretion of large amounts of dilute urine, accompanied by extreme thirst), adrenal hypertension, Addison's disease (caused by destruction of the adrenal glands), dehydration, inappropriate antidiuretic hormone secretion, or other disease involving electrolyte imbalance - Clinical Significance:
In cases of hyponatremia, urine sodium < 10 mEq/L may indicate extrarenal depletion: dehydration (gastrointestinal or sweat loss), congestive heart failure, liver disease or nephrotic syndromes, and prerenal azotemia. Urine sodium > 10 mEq/L may indicate diuretics, emesis, intrinsic renal diseases, Addison’s disease, hypothyroidism, or syndrome of inappropriate antidiuretic hormone (SIADH). In hypothyroidism and in SIADH, sodium and chloride may be >40 mEq/L. In SIADH, urinary sodium usually is >20 mEq/L. - Reference Range:
Adult (M/F): 40 to 220 mEq/L
6 to 10 years (M/F): 41 to 115 mEq/L
11 to 14 years (M/F): 63 to 117mEq/L - Day Run:
Sun-Sat (daily) - Time Run:
As received - Time Reported:
4 hours - Test Type:
URINE
