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Test Name:
Cadmium, Urine, 24-Hour


  • SBMF No:
    23259
  • Performance Lab Name:
    Manual Lab
  • Test Mnemonic:
    U CAD24-
  • ABN:
    Not required
  • CPT Code:
    82300
  • LOINC Code:
    20624-3; 2162-6; 19150-2; 13362-9; 3167-4; 5612-7
  • Test Includes:
    Cadmium
    Creatinine
  • Also Known As:
    Cd
  • Also See:
    23263 – Heavy Metals, Quantitative, Urine, 24-Hour
    23382 – Cadmium, Quantitative, Whole Blood
  • Spec Type:
    Urine, 24-hour
  • Spec Container:
    Plastic, metal-free container with tightly fitting lid
        IMPORTANT: Prior to collection, add 20.0 mL 6N Hydrochloric Acid as preservative
  • Pref Vol:
    20.0 mL aliquot from well-mixed 24-hour collection
    Note: Send urine aliquot with notation of entire 24-hour urine volume on aliquot label and on requisition
  • Min Vol:
    10.0 mL aliquot from well-mixed 24-hour collection
  • Fasting:
    No
  • Patient Prep:
    Instruct patient to avoid contact with preservative in container
    Patient must not void directly into container
    Instruct patient to store container securely away from children
  • Spec Collect:
    Do not collect urine in metal urinals, pans, or metal-based container
    To begin collection of timed specimen, have patient urinate, noting date and exact time
    Discard this first portion of urine, but document date and time of voiding on container label and test requisition as "start" of timed specimen
    Save all urine voided during designated time period, including portion voided at exact end of time period
    Refrigerate entire specimen throughout collection
    Document date and time of final voiding on sample label and requisition as "end" of timed specimen
  • Spec Process:
    Upon completion of collection, mix entire specimen well, and measure 24-hour volume—avoid contact with metal surfaces
    Pour off 20.0 mL urine into separate plastic tube(s)
    Refrigerate urine aliquot and transport refrigerated
    Send urine aliquot with notation of entire 24-hour urine volume on aliquot label and on requisition
  • Spec Store Transport:
    Refrigerated
  • Spec Stability:
    1 week refrigerated (2-8°C)
  • Spec Reject:
    Specimen in contact with metal during collection
  • Spec Remarks:
    Note: 24-hour urine is optimal specimen for testing
  • Methodology:
    Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)
  • Use:
    Detect exposure to cadmium, a toxic heavy metal
  • Clinical Significance:
    The level of trace elements in human body fluids is of great importance for the diagnosis and treatment of a patient’s condition. It is also crucial to monitor individuals who may be exposed to high levels of toxins, such as lead and arsenic.
  • Reference Range:
    24-hour urine: less than 3 µg/day
  • Critical High Value:
    Excessive exposure: greater than 3.0 µg/day
    Severe exposure: greater than 15 µg/day
  • Day Run:
    Mon, Thu
  • Time Run:
    6:00 am
  • Time Reported:
    5:00 pm
  • Test Type:
    CHEMISTRY