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Test Name:
Heavy Metals, Urine, Random
- SBMF No:
23164 - Performance Lab Name:
Manual Lab - Test Mnemonic:
U HEAVYR - ABN:
Not required - CPT Code:
82175; 82300; 83655; 83825 - LOINC Code:
5586-3; 5689-5; 5676-2; 5611-9 - Test Includes:
Arsenic
Cadmium
Mercury
Lead - Also Known As:
Arsenic (As)
Cadmium (Cd)
Lead (Pb)
Mercury (Hg) - Also See:
23360 Arsenic, Quantitative, Urine, Random
23363 Cadmium, Quantitative, Urine, Random
23362 Lead, Quantitative, Urine, Random
23361 Mercury, Quantitative, Urine, Random
23263 Heavy Metals, Quantitative, Urine, 24-Hour - Spec Type:
Urine, random - Spec Container:
Plastic, metal-free container with tight-fitting lid - Pref Vol:
Entire random urine specimen or 10.0 mL aliquot from well-mixed specimen - Min Vol:
5.0 mL aliquot from well-mixed specimen - Fasting:
No - Patient Prep:
Avoid ingestion of seafood for 48 hours before specimen collected - Spec Collect:
Routine random urine collection - Spec Store Transport:
Refrigerated - Spec Stability:
1 week refrigerated (2-8°C) - Spec Remarks:
Note: 24-hour urine is optimal specimen for testing - Methodology:
Inductively Coupled Plasma-Mass Spectrometry - Use:
Screen for heavy metal poisoning and toxic exposure - Clinical Significance:
The level of trace elements in human body fluids is of great importance for the diagnosis and treatment of a patient’s condition.
It is also crucial to monitor individuals who may be exposed to high levels of toxins, such as lead and arsenic. - Reference Range:
Lead:
– Reference Range: 0-80 µg/L
– Industrial Exposure: 0-120 µg/L
– Excessive: 60-400 µg/L
– Toxic: greater than 400 µg/L
Notes:
– Urine lead levels may not correlate with clinical symptoms of lead toxicity or blood lead levels
– A normal urine lead may be observed in lead poisoning
– A whole blood lead test is preferred for lead poisoning
– A 24-hour urine is the optimal specimen for heavy metal testing
Mercury:
– Expected value: less than 20 µg/L
– Possible Toxic concentration: greater than 50 µg/L
Notes:
– The concentration at which toxicity is expressed is widely variable between patients
– 50 µg/L is the lowest concentration at which toxicity is usually apparent
Arsenic:
– Reference Range: 0-35 µg/L
– High Arsenic (seafood) Diet 0-200 µg/L
– Industrial Exposure: 0-600 µg/L
– Urinary excretion of arsenic fluctuates and several negative urines are required to exclude arsenic poisoning
Note: Urine with arsenic value greater than 35 µg/L will be stored for 2 weeks in case physician orders an arsenic fractionation
Cadmium:
– Reference Range: less than 3 µg/L - Day Run:
Mon, Tue, Thu, Fri - Time Run:
8:00 am - Time Reported:
5:00 pm - Test Type:
CHEMISTRY
