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Test Name:
Helicobacter pylori Urease Breath Test


  • SBMF No:
    23063
  • Performance Lab Name:
    Manual Lab
  • Test Mnemonic:
    H PYL BT
  • ABN:
    Not required
  • CPT Code:
    83013
  • LOINC Code:
    29891-9
  • Spec Type:
    Breath sample
  • Spec Container:
    BreathTek™-UBiT Collection Kit
  • Fasting:
    Yes
  • Patient Prep:
    Note: Test cannot be performed on any patient less than 18 years of age
    Patient should fast at least 1 hour prior to sample collection
    Patient should be restricted from antimicrobials, proton pump inhibitors, or bismuth preparations for 2 weeks prior to the test to prevent false negative results
  • Spec Collect:
    Two (2) breath samples are to be collected following instructions in collection kit
    A baseline breath sample is collected before administration of "Pranactin-Citric"
    A post-dose sample is collected 15 minutes after ingestion of "Pranactin-Citric"
  • Spec Store Transport:
    Room temperature
  • Spec Stability:
    1 week room temperature (20-30°C)
  • Spec Remarks:
    Age, gender, height, and weight are required to calculate urea hydrolysis rate.
    The drug component, "Pranactin-Citric", contains phenylalanine.
  • Methodology:
    Spectrophotometry
  • Use:
    Measurement of excess 13CO2 in the breath is a widely accepted technique for the detection of the presence or absence of H. pylori, the bacterium responsible for more than 80% of peptic ulcer disease. Breath testing is one of only a few techniques that can detect an active infection. The presence of H. pylori can be verified in symptomatic patients and drug therapy which is more than 90% effective can be prescribed. A second test after completion of therapy can verify the eradication of H. pylori.
  • Reference Range:
    Adult (Equal to or greater than 18 years old): Cutoff point at DOB (Delta Over Baseline) of 2.4 to distinguish H. pylori infection positive and negative results
    Note: Test cannot be performed on any patient less than 18 years of age
  • Additional Test Info:
    A drug administration fee (CPT 83014) is added for all samples at SBMF facilities
  • Day Run:
    Mon-Fri
  • Time Run:
    8:00 am
  • Time Reported:
    5:00 pm
  • Test Type:
    INFECTIOUS ORGANISM